Private Sub MyListView_AfterLabelEdit(ByVal sender As Object, ByVal e As System.Windows.Forms.LabelEditEventArgs) Handles listView1.AfterLabelEdit

   ' Determine if label is changed by checking to see if it is equal to Nothing.
   If e.Label Is Nothing Then
      Return
   End If
   ' ASCIIEncoding is used to determine if a number character has been entered.
   Dim AE As New ASCIIEncoding()
   ' Convert the new label to a character array.
   Dim temp As Char() = e.Label.ToCharArray()

   ' Check each character in the new label to determine if it is a number.
   Dim x As Integer
   For x = 0 To temp.Length - 1
      ' Encode the character from the character array to its ASCII code.
      Dim bc As Byte() = AE.GetBytes(temp(x).ToString())

      ' Determine if the ASCII code is within the valid range of numerical values.
      If bc(0) > 47 And bc(0) < 58 Then
         ' Cancel the event and return the lable to its original state.
         e.CancelEdit = True
         ' Display a MessageBox alerting the user that numbers are not allowed.
         MessageBox.Show("The text for the item cannot contain numerical values.")
         ' Break out of the loop and exit.
         Return
      End If
   Next x
End Sub