' This event handler manually raises the CellValueChanged event
' by calling the CommitEdit method.
Sub dataGridView1_CurrentCellDirtyStateChanged( _
    ByVal sender As Object, ByVal e As EventArgs) _
    Handles dataGridView1.CurrentCellDirtyStateChanged

    If dataGridView1.IsCurrentCellDirty Then
        dataGridView1.CommitEdit(DataGridViewDataErrorContexts.Commit)
    End If
End Sub

' If a check box cell is clicked, this event handler disables  
' or enables the button in the same row as the clicked cell.
Public Sub dataGridView1_CellValueChanged(ByVal sender As Object, _
    ByVal e As DataGridViewCellEventArgs) _
    Handles dataGridView1.CellValueChanged

    If dataGridView1.Columns(e.ColumnIndex).Name = "CheckBoxes" Then
        Dim buttonCell As DataGridViewDisableButtonCell = _
            CType(dataGridView1.Rows(e.RowIndex).Cells("Buttons"), _
            DataGridViewDisableButtonCell)

        Dim checkCell As DataGridViewCheckBoxCell = _
            CType(dataGridView1.Rows(e.RowIndex).Cells("CheckBoxes"), _
            DataGridViewCheckBoxCell)
        buttonCell.Enabled = Not CType(checkCell.Value, [Boolean])

        dataGridView1.Invalidate()
    End If
End Sub