You can configure a custom keystore to use for your debug builds (the ones that happen when you click Run...) in Eclipse by going to Preferences -> Android -> Build and entering the file name in the "Custom debug keystore" option.
However, it has the caveat that it must follow the same rules as a traditional debug keystore, mainly:
- The keystore password must be "android"
- It must contain a key named "androiddebugkey"
- That key's password must be "android"
Therefore, while it is possible to sign your apps in debug with the same keystore as you Export with, it requires your production keystore to look like a debug store, which makes it less secure if someone got ahold if the file (it would be easier to inspect and guess the passwords).
HTH
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